Know the broad categories
Acetoxy silicones are common for general sealing but may not be compatible with every metal or finish. Neutral-cure products are often chosen for more sensitive substrates. Polyurethane windscreen adhesive is a distinct category and should not be substituted with a general silicone sealant.
Check the working conditions
Consider whether the joint is indoors or outside, exposed to water or UV, and likely to move. Check the application-temperature range, bead size and cure schedule on the product label. A stated surface-skin time is not the same as a through-cure time.
Plan for the finish
Silicone sealants are generally not paintable. Remove old material where needed, clean and dry the surfaces, mask edges if a neat line matters, and tool the bead before a skin forms. Use the manufacturer’s recommended cleaner and protective measures.
Read the product data sheet for the exact substrate, conditions and cure—not just the headline use.
This page is an original, concise educational summary based on the linked source article. Product specifications can change; consult the manufacturer’s current instructions before use.